Clinical Studies
Zhonghua Yi: Curative Effect of alpha-lipoic acid on peripheral neuropathy in type 2 diabetes:a clinical study. 87(38):2706-9, 2007
Ruessmann HJ: Switching from pathogenetic treatment with alpha-lipoic acid to gabapentin and other analgesics in painful diabetic neuropathy: a real-world study in outpatients. J Diabetes Complications. 23(3):174-7, 2009
Bell David: Metformin-induced Vitamin B12 deficiency presenting as a peripheral neuropathy. South Med J 103(3): 265-267, 2010
Smith RG: Painful Diabetic Peripheral Neuropathy. J Am Podiatric Med Assoc 97: 394, 2007
Attal N, Bouhassira D: Mechanisms of pain in peripheral neuropathy. Acta Neurol Scand Suppl 173: 12, 1999
The Diabetes Control and Complications Trial Research Group. The effect of intensive diabetes therapy on the development and progression of neuropathy, Ann Intern Med 122: 561, 1995
Halat KM, Dennehy CE. Botanicals and dietary supplements in diabetic peripheral neuropathy. J Am Board Fam Pract. 16: 47, 2003
NIH State-Of-The-Science Conference Statement on Multivitamin/Mineral Supplements and Chronic Disease Prevention. NIH Consensus and State-Of-The-Science Statements 23, (2): May 15-17, 2006
Nagamatsu M, Nickander KK, Schmelzer JD, et al. Lipoic acid improves blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care 16: 1160, 1995
Low PA, Nickander KK, Tritschler HJ. The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy. Diabetes 46: S38, 1997
Reljanovic M, Reichel G, Rett K, et al. Treatment of diabetic polyneuropathy with antioxidant thioctic acid (alpha lipoic acid): a two-year-multi-center randomized double blind placebo-controlled trial (Aladin II). Alpha Lipoic Acid in Diabetic Neuropathy. Free Radic Res 31: 171, 1999
Ruhnau KJ, Meissner HP, Finn JR, et al. Effects of 3-week oral treatment with antioxidant thioctic acid (alpha lipoic acid) in symptomatic diabetic polyneuropathy. Diabet Med16: 1040, 1999
Berrone E, Beltramo E, Solimine C, et al. Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose. J Biol Chem 281: 9307, 2006
Stracke H, Gaus W, Achenbach U, et al. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomized, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes. 116: 600, 2008
McCan YJ, Davis RF. Serum pyridoxal concentrations in patients with diabetic neuropathy. Aust NZ J Med 8: 259, 1978
Jones CL, Gonzalez V. Pyridoxine deficiency: a new factor in diabetic neuropathy. J Am Podiatry Assoc. 68: 646, 1978
Tutuncu NB, Bayraktar M, Varli K. Reversal of defective nerve conduction with vitamin E supplementation in type 2 diabetes: a preliminary study. Diabetes Care 11: 1915, 1998